(Close): Drugmaker Shire was the biggest riser on the London stock market after a much-anticipated hostile bid from a rival finally emerged.
Its share price soared by 17% after US company AbbVie said it had made a bid approach which Shire's board had rejected.
That helped push the benchmark FTSE 100 index up 17 points, or 0.25%, to 6,825.20.
One of the biggest losers was energy firm BG Group, which fell 1.63%.
On the currency markets, the pound fell 0.17% against the dollar to 1.7011, and was unchanged against the euro at 1.2522 euros.
