(Close): US stocks closed down on Monday, but were off their lows of the day, as talks failed between Greece and its creditors over the weekend.
The Dow Jones industrial average fell by 107 points, or 0.6%, to 17,791.60, while the broader S&P 500 index dropped 10 points, or 0.5%, to 2,084.43.
The tech-heavy Nasdaq slipped 21 points, or 0.4% to 4,5029.97.
A European Commission spokesman said while progress was made at Sunday's talks "significant gaps" remained.
The president of the European Central Bank, Mario Draghi, said on Monday that the "ball lies squarely in the camp" of the Greek government.
Meanwhile a manufacturing survey in the US added to economic concerns. The Federal Reserve said manufacturing output fell by 0.2% in May, hurt by the stronger dollar and a drop in spending by energy companies.
In company news, shares in the retailer Target were up more than 1% after the pharmacy CVS said it would buy Target's pharmacy and clinics business for $1.9bn.
The deal gives CVS, the country's second-largest drugstore chain a retail presence in new markets like Seattle, Denver, and Salt Lake City. CVS shares were up just 0.3%.
