Connor Jennings's late goal rescued a point against Guiseley but Wrexham have now gone six games without a win in the National League.
Gavin Rothery's low shot beat Cameron Belford at the near post to put Guiseley ahead before two Dominic Vose goals put Wrexham in control.
Substitute Liam Dickinson equalised and Adam Boyes scored Guiseley's third before Rothery was sent-off late on.
But captain Jennings' stoppage time strike denied Guiseley, who stay 18th.
Wrexham manager Gary Mills told BBC Radio Wales:
"It's as a poor as we've been. We were second best tonight.
"We're scoring goals but we're not keeping clean sheets and it's costing us dearly. You don't win anything if you don't keep clean sheets.
"It's got to change and we might have to do things a bit uglier just to get a clean sheet."
- Published7 June 2019
- Published20 June 2016
