Gloucester make nine changes from last Thursday's opening loss at Pau for the visit of Agen in the Challenge Cup.

James Hanson and Ben Vellacott make their first starts for the Cherry and Whites, while Gareth Denman and Charlie Beckett get first European starts.

England number eight Ben Morgan (calf) returns for the first time since his injury at the start of the season.

Agen were 45-10 winners over Zebre in the opening round in Pool 3 and top the standings thanks to their bonus point.

Gloucester: Woodward; Purdy, Trinder, Williams, Halaifonua; Burns, Vellacott; Hohneck, Hanson, Denman, Savage (capt), Beckett, Polledri, Ludlow, Morgan.

Replacements: Hibbard, Orr, Afoa, Clarke, Rowan, Heinz, Twelvetrees, Braley.

Agen: Lo Tolot; Lu Tolot, Conduche, Dubois, Holder; Russell, Verdu; Ahaouche, Martinez, Tufele, Van der Merwe, Braendlin (capt), Jegerlhener, Tanga, Ghirard.

Replacements: Peyri, Butler, Chabeaudie, Touchkaieff, Fouyssac, Lanave, Farah, Saurs.